Putting Science to Work

Discovery Biology

Syngene has a sophisticated biology facility with high-end instrumentation. We have an experienced team with proven track record of supporting discovery and development programs under biology capabilities.

Some of the key instruments are listed below:

Molecular Biology
  • Automated DNA sequencer- ABI 3730 XL, ABI 3130XL
  • Thermal Cyclers
  • Real-Time PCR instruments (ABI 96 well & 384 well formats)
  • Pulsed field electrophoresis
  • Gene Pulser
  • Gel Documentation Systems
  • Nano Drop Spectrophotometer
Microbiology
  • Bench Top Fermenters
  • Biosafety Cabinets- BSL I & II
  • Incubators and Incubator Shakers
  • Vitek 2 compact

Cell Biology
  • FACS Calibur
  • FACS Accuri
  • FACS JAZZ
  • Clone Pix
  • Gene Pulser Xcell
  • Amaxa 4D Nucleofector
  • Biosafety Cabinets- BSL II
  • CO2 Incubators & Shakers
  • Phase Contrast & Fluorescence Microscopes (Apotome)
  • Spinner Flasks
  • Wave Bioreactor
  • Lab Scale Bioreactors
  • Automated Cell Counter
  • -156°C cryo freezer
  • Flow Cytometer (BD)
Protein Purification
  • ÄKTA- FPLCs (START,Primes, Purifiers & Explorers)
  • BioRad- NGC
  • High speed centrifuges
  • Ultra centrifuge
  • Sonifier
  • Micro-Fluidizer
  • Lyophilizer
  • Tangential/ cross flow concentrators
  • Columns & resins covering broad range of chromatographic separations
Protein Crystallography
  • Mosquito 5-deck crystallography robot
  • Polarizing light microscope
  • Cryo Storage
  • Other Crystallography tools
Analytical
  • BIAcore T200
  • Imaging Capillary Electrophoresis (ICE)
  • Capillary Zone Electrophoresis (CZE)
  • IEF
  • ELISA reader (96 well format)
  • Karl Fischer Coulometric Titrator
  • Chemi Doc-XRS (Bio-Rad)
  • RP-HPLC
  • Image Quant 300; Image Scanner
  • Mass Spectrometry (MALDI/TOF-TOF)
  • ESI-MS with HMD
  • Octet RED
  • WES (WesternBlotting)
Screening/ assay biology

Liquid Handling Systems/Pipetting stations

  • Freedom Evo 150 (Tecan)
  • epMotion (Eppendorf)
  • Multidrop Combi (Thermo)
  • 96 well plate washers

Multimode plate readers with stackers

  • Plate Chameleon V (Hidex)
  • TopCount Nxt HTS (Perkin Elmer)
  • Spectramax PLUS (Molecular Devices)
  • EnVision Multilabel reader (Perkin Elmer)
  • FlexStation 3 (Molecular Devices)
  • Multiplex
Bioanalytical
  • HPLCs (Agilent 1200, Shimaduzu Prominence UFLC)
  • LC-MS/MS (API2000, 3200 and 4000)
  • TurboVap LV
  • API- 2000, 3200, 4000, 4000-Q-Trap (Lightsight Software)

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