Putting Science to Work
Syngene

Publications

Syngene is dedicated to providing biotech professionals with the most comprehensive selection of publications. Get in-depth information from the articles written by our scientists.

Posters/Presentations:
  • 2017
    • A Normal Phase Chiral HPLC Method for the Separation of Eight Isomers of Core +OMe. "Nilesh Joshi, Balaji D, Athimoolam Pillai, Justine Paulose, Jessica Tan, Laura Blue, Jason Tedrow, Bob Farrell" Amgen Oral and poster presentation was given on 21 June and poster on 20 June 2017 at held on HPLC 2017 international Symposium, 18 to 22 June 2017
  • 2012
    • "Recyclable Silica Supported Palladium Catalyst for Suzuki-Miyaura Cross-Coupling Reactions in Water", Shanmugham Ganesamoorthy et al., 40th International Conference on Coordination Chemisty to be held at Universitat de València, Spain, during September 9 to 13, 2012.
    • "New Highly Selective FAK Inhibitors", Timo Heinrich et al., European Federation for Medicinal Chemistry (EFMC)- 22nd International Symposium on Medicinal Chemistry held at Berlin, Germany, September 2 - 6, 2012
  • 2011
    • "Propylphosphonic anhydride (T3P): A Convenient and Versatile Reagent in Organic Synthesis", Invited Lecture by John Kallikat Augustine. International Conference on Synthetic and Structural Chemistry held at Mangalore University, Mangalore, Karnataka, India during December 8-10, 2011.
  • 2010
    • "Click" immobilization of Ru(II) and Ru(III) catalysts over Silica. Ganesamoorthy et al., National Conference on Recent Trends in Chemical Research held at National Institute of technology, Surathkal, Karnataka, India during March 8 to 10, 2010.
  • 2008
    • "Mild oxidation of alcohols to carbonyl compounds with periodic acid catalyzed by [Ru(acac)2(CH3CN)2]PF6 in water", S.Ganesamoorthy et al., at 10th CRSI national symposium in chemistry held at Indian Institute of Science, Bangalore, India from February 1 to 3, 2008.
Publications/Patents:
  • 2017

        • Bicyclic Heterocycles as inhibitors of cholesterol ester transfer protein Shao, P. P.; Kattipally, R. R.; Vachal, P.; Thatai, Jayanth T.; Sarkar, Sujit K. Patent WO 2017/011279
        • Room Temperature Carbonylation of (Hetero) Aryl Pentafluorobenzenesulfonates and Triflates using Palladium‐Cobalt Bimetallic Catalyst: Dual Role of Cobalt Carbonyl Joseph, J. T.; Sajith, A. M.;  Ningegowda, R. C.;  & Shashikanth, S. Adv. Synth. Catal., 359 419 – 425
        • Scalable Synthesis of 6,6-Dimethylbicyclo[3.1.0]hexan-3-one "Steven M. Mennen Athimoolam Arunachalampillai Deborah M. Choquette Harikrishna Mupalla Krishna Sheena" Amgen Synlett 28 A-E 2.151 Read More
        • POLYMORPHS OF S-ETHYLISOTHIOURONIUM DIETHYLPHOSPHATE No authors from Syngene are included in the patent TrioxBio. Inc U.S.Provisional Patent Application Attorney Docket: TRX/003 USP
        • Novel Composition Geetha Thanga MARIAPPAN; Anusha GOPISETTY and Prashanth VASANTHAKUMAR GSK Indian Patent Application number 201711007796

  • 2016

    • Monocyclic isoxazolines as inhibitors of cholesterol ester transfer protein Shao, P. P.; Ye, F.; Vachal, P.; Thatai, Jayanth T. Patent WO 2016/018729
    • Imidazolopyrimidine derivatives Hoelzemann, G.; Dorsch, D.; Wegener, A.; Poeschke, O.; Busch, M.; Seenisamy, J. Patent US 2016/0002242A1
    • Heteroaryl compounds as BTK inhibitors and uses thereof Gaillard, P.; Seenisamy, J.; Liu-Bujalski,L.; Caldwell, R.D.; Potnick, J.; Qiu, H.; Neagu, C.; Jones, R.; Won,; A.C.; Goutopoulos, A,; Sherer, B.A.; Johnson, T.L.; Garderberg, A. Patent US 2016/0096834A1
    • 9-(Aryl or Heteroaryl)-2-(pyrazolyl, pyrrolidinyl or cyclopentyl)aminopurine derivatives as anticancer agents Hoelzemann, G.; Dorsch, D.; Wegener, A.; Poeschke, O.; Busch, M.; Seenisamy, J. Patent EP 2 964 648 B1
    • Glycosidase Inhibitors Quattropani Anna, Kulkarni Santosh S & Giri Awadut Gajendra Patent WO 2016/030443 
    • Four ring achiral ferroelectric liquid crystals of 1,2,4-oxadiazoles: synthesis and characterization Mahabaleshwara, S.; Poornima, B.; Sangeetha, G. B.; Potukuchi, D. M. & Srinivasulu M Liq., Cryst., 43 400 - 410
    • Tetrahydro-2-naphthyl and 2‑Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial Activity Kokkonda, S.; Deng, X.; White, K.L.; Coteron, J.M.; Marco, M.; Heras, L.L.; White, J.; Mazouni, F.E.; Tomchick, D.R.; Manjalanagara, K.; Rudra, K.R.; Chen, G.; Morizzi, J.; Ryan, E.; Kaminsky, W.; Leroy, D.; Martínez,M.S.M.; Jimenez-Diaz, M.B.; Bazaga, S.F.; Barturen, I.A.; Waterson, D.; Burrows, J.N.; Matthews, D.; Charman, S.A.; Phillips, M.A.; & Rathod, P.K.; J. Med. Chem., 59 5416 − 5431
    • A convenient one-pot synthesis of triazolopyridine and related heterocycle fused-triazole analogs through copper catalyzed oxidative cyclization strategy Srinivasan, R., Ruso, J. S., Nagarajan, N. S., Kumaran, R. S. and Manickam, G J. Heterocycl. Chem., 53 606 - 614
    • Hit-to-Lead Studies for the Antimalarial Tetrahydroisoquinolone Carboxanilides Floyd, D.M.; Stein, P.; Wang, Z.; Liu, J.; Castro, S.; Clark, J. A.; Connelly, M.; Zhu, F.; Holbrook, G.; Matheny, A.; Sigal, M. S.; Min, J.; Dhinakaran, R.; Krishnan, S.; Bashyam, S.; Knapp, S.; & Guy R. K. J. Med. Chem. 59 7950 – 7962
    • White Paper- A report on Troglitazone analysis using the HeptoxTM Virtual Liver platform, March-2016
    • White Paper- A report on TAK-875 analysis using the HeptoxTM Virtual Liver platform, February-2016
    • “Four ring achiral ferroelectric liquid crystals of 1,2,4-oxadiazoles: synthesis and characterization” 45) Mahabaleshwara, S.; Poornima, B.; Sangeetha, G. B.; Potukuchi, D. M.; Srinivasulu M. Liq.,Cryst., 2016, 43, 400-410. (DOI: 10.1080/02678292.2015.1116626.)
    • “Tetrahydro-2-naphthyl and 2 Indanyl Triazolopyrimidines Targeting Plasmodium falciparum Dihydroorotate Dehydrogenase Display Potent and Selective Antimalarial Activity” 46) Kokkonda, S.; Deng, X.; White, K.L.; Coteron, J.M.; Marco, M.; Heras, L.L.; White, J.; Mazouni, F.E.; Tomchick, D.R.; Manjalanagara, K.; Rudra, K.R.; Chen, G.; Morizzi, J.; Ryan, E.; Kaminsky, W.; Leroy, D.; Martínez,M.S.M.; Jimenez-Diaz, M.B.; Bazaga, S.F.; Barturen, I.A.; Waterson, D.; Burrows, J.N.; Matthews, D.; Charman, S.A.; Phillips, M.A.; Rathod, P.K.; J. Med. Chem. 2016, 59, 5416−5431. DOI: 10.1021/acs.jmedchem.6b00275.
    • “A convenient one-pot synthesis of triazolopyridine and related heterocycle fused-triazole analogs through copper-catalyzed oxidative cyclization strategy” 447) Srinivasan, R., Ruso, J. S., Nagarajan, N. S., Kumaran, R. S. and Manickam, G.J, Heterocycl. Chem. (Article in press). DOI 10.1002/jhet.2331
    • “Treatment of Chagas Disease”, WO2015/189595A1 (2015) Kahnberg, P.; Johansson, Nils Gunnar; Gilbert, Ian; Hampton, Shahienaz; Harrison, Justin; Sarkar, Sandipan; Gonzalez, Dolores.
    • “Monocyclic isoxazolines as inhibitors of cholesterol ester transfer protein”, 20) WO 2016/018729 (2016) Shao, P. P.; Ye, F.; Vachal, P.; Thatai, Jayanth T
    • “US 2016/0002242A1(2016) Hoelzemann, G.; Dorsch, D.; Wegener, A.; Poeschke, O.; Busch, M.; Seenisamy, J.; Imidazolopyrimidine derivatives"
    • “22) US 2016/0096834A1 (2016) ; Gaillard, P.; Seenisamy, J.; Liu-Bujalski,L.; Caldwell, R.D.; Potnick, J.; Qiu, H.; Neagu, C.; Jones, R.; Won,; A.C.; Goutopoulos, A,; Sherer, B.A.; Johnson, T.L.; Garderberg, A.; Heteroaryl compounds as BTK inhibitors and uses thereof".

  • 2015

    • SPRINKLE FORMULATIONS OF ACAMPROSATE Steven L. Johns, Kenneth G. Payie, Badrinath R. Doniparthi, Shivaraj B. Munianjanappa Confluence Pharma US Patent 62/156, 842 62/260, 161
    • "Aryl/heteroaryl pentafluorobenzenesulfonates (ArOPFBs): new electrophilic coupling partners for room temperature Suzuki-Miyaura cross-coupling reactions” ,38) Joseph, J. T.; Sajith, A. M.; Ningegowda, R. C.; Nagaraj, A.; Rangappa, K. S.; Shashikanth, S.;Tetrahedron Letters. 2015, 56, 5106-5111. DOI: 10.1016/j.tetlet.2015.07.033 .
    • “Palladium catalyzed C-5 arylation of 2-fused triazole substituted thiophene and furan using aryl iodide through C-H activation strategy” ,39) Srinivasan, R., Kumaran, R. S.; Nagarajan, N. S. Catal. Commun. 2015, 58, 187-189. DOI: 10.1016/j.catcom.2014.09.007.
    • “T3P as an efficient cyclodehydration reagent for the one pot synthesis of 2-amino-1,3,4-oxadiazoles” , 40) Ilangovan, A.; Saravanakumar, S. and Umesh. S. J. Chem. Sci. 127, 2015, 797-801. DOI: 10.1007/s12039-015-0834-x.
    • “Novel biphenyl-substituted 1,2,4-oxadiazole ferroelectric liquid crystals: synthesis and characterization”. 41) Mahabaleshwara, S.; Potukuchi, D. M.; Girish, S. R.; Poornima, B.; Sangeetha, G. B.; Srinivasulu, M ,Beilstein J. Org. Chem. 2015, 11, 233–241. (DOI: 10.3762/bjoc.11.26.).
    • “Synthesis of Isoquinoline Derivatives from β-Hydroxyarylethanamides” .42) Suresh, R.; Muthusubramanian Synth. Commun. 2015, 45, 1696-1703. DOI: 10.1080/00397911.2015.1042590.
    • “Investigation on the reactivity of α-azidochalcones with carboxylic acids: Formation of α-amido-1,3-diketones and highly substituted 2-(trifluoromethyl)oxazoles”, .43) Rajaguru, K.; Mariappan, A.; Suresh, R.; Muthusubramanian, S.Beilstein J. Org. Chem. 2015, 11, 2021–2028. DOI: 10.3762/bjoc.11.219.
    • "A novel pyrazolopyridine with in vivo activity in Plasmodium berghei and Plasmodium falciparum-infected mouse models from structure-activity relationship studies around the core of recently identified antimalarial imidazopyridazines", .444) Le Manach, C.; Paquet, T.; Brunschwig, C.; Njoroge, M.; Han, Z.; Gonzalez C. D.; Bashyam, S.; Dhinakaran, R.; Taylor, D.; Reader, J.; Botha, M.; Churchyard, A.; Lauterbach, S.; Coetzer, T.; Birkholtz, L.; Meister, S.; Winzeler, E.; Waterson, D.; Witty, M.; Wittlin, S.; Jimenez D., Maria B.; Santos M. M.; Ferrer, S.; Angulo-Barturen, I.; Street, L.; Chibale, K.; J. Med. Chem. 2015, 58, 8713−8722. DOI: 10.1021/acs.jmedchem.5b01605.
    • “Identification and Deconvolution of Antimalarial Compounds Cross-Resistance Signals using Multidrug-Resistant Plasmodium falciparum Strains” ,Monika C.; Christian, S.; Sibylle, S.; Elizabeth, B.; Donelly, A.V; Schalkwyke, K. J.; Wicht, N. H.; Anil S.; Bashyam, S.; Singh, S.; Oliver, S.G.; Egan, T.J.; Malhotra, P.; Sutherland, C.J.; Beck, P.H.; Wittlin, S.; Spangenberg, T.; Ding, X. C.;Antimicrobial Agents and Chemotherapy, 2015, 59, 2.
    • “Aryl/heteroaryl pentafluorobenzenesulfonates (ArOPFBs): new electrophilic coupling partners for room temperature Suzuki-Miyaura cross-coupling reactions” ,Joseph, J. T.; Sajith, A. M.; Ningegowda, R. C.; Nagaraj, A.; Rangappa, K. S.; Shashikanth, S.; Tetrahedron Letters. 2015, 56, 5106-5111. DOI: 10.1016/j.tetlet.2015.07.033.
    • “Palladium catalyzed C-5 arylation of 2-fused triazole substituted thiophene and furan using aryl iodide through C-H activation strategy” ,Srinivasan, R., Kumaran, R. S.; Nagarajan, N. S.Catal. Commun. 2015, 58, 187-189. DOI: 10.1016/j.catcom.2014.09.007.
    • “A convenient one-pot synthesis of triazolopyridine and related heterocycle fused-triazole analogs through copper catalyzed oxidative cyclization strategy” ,Srinivasan, R., Ruso, J. S., Nagarajan, N. S., Kumaran, R. S. and Manickam, G.J. Heterocycl. Chem. (Article in press). DOI 10.1002/jhet.2331 .
    • “Novel pyrrolidine derived beta 3 adrenergic receptor agonists” , 1) WO2015/050798 (2015) Barr, Kenneth, Jay; Scott, Mark, E; Thompson, Christopher, F; Anthony, Neville; Cammarano, Carolyn, Michelle; BAKSHI, Raman, Kumar; MOHANTY, Subhendu, Kumar; Korapala, Chandra, Sekhar; Latthe, Prashant, R; Kambam, Vyjayanthi, N; Sarkar, Sujit, Kumar; Thatai, Jayanth, Thiruvellore.
    • “Self-immolative linkers containing mandelic acid deivatives , drug-ligand conjugates for targeted therapies and uses thereof” ,2) WO2015/038426 (2015) VENKATESAN, A. M.; SMITH, R. A.; DAMLE, N. K.; BAKSHI, R. K.; ODEDRA, A. V.; KUMAR, S.
    • “Glycosidase Inhibitors” ,EP14188599 (2015) Quattropani, A.; Kulkarni, S.; Giri, A.
    • “4,7-Phenanthroline containing polymer and organic electronic device” ,4) WO082879A1 (2015) Jeremy, B.; Tania, Z.; Rajesh Kumar, J.; Shanmugasundaram, K.

  • 2014

    • “Screening and hit evaluation of a chemical library against blood-stage Plasmodium falciparum” ,Avery, V.M.; Bashyam.S.; Burrows, J.N.; Duffy, S.; Papadatos,G.; Puthukkuti, S.; Sambandan.Y.; Singh,S.; Spangenberg, T*.; Waterson, D.; Willis, P.Malaria Journal 2014, 13:190.
    • “Enantioselective Synthesis and Physicochemical Properties of Libraries of 3-Amino- and 3-Amidofluoropiperidines” ,Orliac, A.; Routier, H.; Charvillon, F.B.; Sauer, W.H.B; Bombrun, A.; Kulkarni, S.; Pardo, D.G.; Cossy, J.Chemistry - A European Journal, 2014, 20 (13), 3813-3824.
    • “TiCl4-mediated olefination of aldehydes with acetic acid and alkyl acetates: A stereoselective approach to (E)-α,β-unsaturated carboxylic acids and esters” ,Augustine, J. K.; Boodappa, C.; Venkatachaliah, S.; Mariappan, A.Tetrahedron Lett. 2014, 55, 3503-3506. DOI: 10.1016/j.tetlet.2014.04.098 .
    • “α-Haloacrylates as acceptors in the [3 + 2] cycloaddition reaction with NaN3: an expedient approach to N-unsubstituted 1,2,3-triazole-4-carboxylates”,Augustine, J. K.; Boodappa, C.; Venkatachaliah, S.Org. Biomol. Chem. 2014, 12, 2280-2288. DOI: 10.1039/C3OB42276C.
    • “Highly efficient homogeneous and heterogenized ruthenium catalysts for transfer hydrogenation of carbonyl compounds”,Ganesamoorthy, S., Jerome, P., Shanmugasundaram, K.; Karvembu, R.RSC adv. 2014, 4, 27955-27962. DOI: 10.1039/C4RA04136D .
    • “Pd-catalyzed oxidative C-H arylation of heterocycle embedded thiophene/furan with aryl boronic acid/ester” ,Srinivasan, R., Kumaran, R. S.; Nagarajan, N. S. RSC Adv. 2014, 4, 47697-47700. DOI 10.1039/C4RA06055E .
    • “Palladium catalyzed C-5 arylation of 2-fused triazole substituted thiophene and furan using aryl iodide through C-H activation strategy”,Srinivasan, R., Kumaran, R. S.; Nagarajan, N. S. Catal. Commun. 2015, 58, 187-189. DOI: 10.1016/j.catcom.2014.09.007.
    • “Alpha hydroxyl amides”,WO2014/048547A1 (2014); Muzerelle, M.; Swinnen, D.; Seenisamy, J.
    • “Alpha-Amino boronic acid derivatives, selective immunoproteasome inhibitors”,US2014/0364396A1 (2014) Swinnen, D.; Crosignani, S.; Seenisamy, J.; Morandi, F.
    • “9-(Aryl or Heteroaryl)-2-(pyrazolyl, pyrrolidinyl or cyclopentyl)aminopurine derivatives as anticancer agents”, WO2014/135245A1 (2014) Hoelzemann, G.; Dorsch, D.; Wegener, A.; Poeschke, O.; Busch, M.; Seenisamy, J.
    • “Novel compounds that are ERK inhibitors”, 10) WO2014/052563 Wilson, K. J.; Witter, D. J.; Siliphaivanh, P.; Lipford, K.; Sloman, D.; Falcone, D.; O'Boyle, B.; Mansoor, U. F.; Lim, J.; Methot, J. L.; Boyce, C.; Chen, L.; Daniels, M. H.; Fevrier, S.; Huang, X.; Kurukulasuriya, R.; Tong, L.; Zhou, W.; Kozlowski, J.; Maletic, M. M.; Shinkre, B. A.; Thatai, J. T.; Bakshi, R. K.; Karunakaran, G. B.
    • “Novel compounds that are ERK inhibitors” , Mansoor, U. F.; Fevrier, S.; Huang, X.; Kurukulasuriya, R.; Richard, J. E.; Tang, S.; Boyce, C.; Kozlowski, J.; Bakshi, R. K.; Karunakaran, G. B.
    • “Tetraaza-cyclopenta[A]indenyl derivatives” , WO2014/198808 (2014) Quattropani, A.; Kulkarni, S.; Murugesan, K.; Banerjee, J.
    • “Preparation of pyridazinone-amides derivatives for treating inflammatory disease, autoimmune disorder, cancer or multiple sclerosis” ,WO2014/121931 (2014) Jorand-Lebrun, C.; Kulkarni, S.; Crosignani, S.
    • “Macrocyclic pyridazinone derivatives as IRAK inhibitors and their preparation”,WO2014/121942 (2014) Jorand-Lebrun, C.; Kulkarni, S.; Christmann-Franck, S.

  • 2013

    • “Cyclic amides as MetAP-2 Inhibitors”,US2015031670A1 (2013) Heinrich, T.; Zenke, F.; Krier, M.; Friese-Hamim, M.; Seenisamy, J.

  • 2012
    • “Spiroalkene carboxamide derivatives and their use as chemokine receptor modulators and their preparation”.WO2012/130915 (2012) Jorand-Lebrun, C.; Swinnen, D.; Gerber, P.; Kulkarni, S.
    • “Synthesis and structure-activity relationship studies of antimalarial 3,5-substituted 2-aminopyridines’,González Cabrera, D.; Douelle, F.; Younis, Y.; Feng, T.-S.; Le Manach, C.; Nchinda, A. T.; Street, L. J.; Scheurer, C.; Kamba, J.; White, K. L.; Montagnat, O. D.; Ryan, E.; Katneni, K.; Zabiulla, K. M.; Joseph, J. T.; Bashyam, S.; Waterson, D.; Witty, M. J.; Charman, S. A.; Wittlin, S.; Chibale, K.J. Med. Chem. 2012, 55, 11022−11030.
    • “Selective synthesis of 5,6-dihydrophenanthridines, 5,6-dihydrobenzo[c][1,8]naphthyridines and their fully aromatized analogues via the Pictet-Spengler reaction mediated by peptide coupling agent propylphosphonic anhydride (T3P)” 15) Augustine, J. K.; Bombrun. A.; Alagarsamy, P.; Jothi. A. Tetrahedron Lett. 2012, 53, 6280-6287. DOI: 10.1016/j.tetlet.2012.09.034
    • “Prodrugs of Inhibitors of Plasma Kallikrein” WO2012/142308A1 (2012) Sinha, S.; Chilcote, T.J.; Suresh, J.R.; Narasimhan, S.
    • "SnCl2-Catalyzed Selective Atom Economic Imino Diels-Alder Reaction: Synthesis of 2-(1H-Pyrrolo[2,3-b]pyridin-3-yl) quinolones", Govindasamy Manickam et al., J. Org. Chem., 2012, 77 (3), 1468–1476.
    • "A facile stereoselective synthesis of julolidine hybrid analogs via domino knoevenagel intramolecular hetero Diels Alder reaction", Atanu Ghoshal et al., Tet. Lett. 2012, 53, 1748-1752.
    • "3,5-Diaryl-2-aminopyridines as a novel class of orally active antimalarials demonstrating single dose cure in mice and clinical candidate potential", Yassir Y Younis et al., J Med Chem 55(7):3479-87 (2012)
    • "Highly efficient and chemoselective acetalization and thioacetalization of aldehydes catalyzed by propylphosphonic anhydride (T3P) at room temperature", John Kallikat Augustine et al., Tetrahedron Lett. 2012, 53, 5030-5033.
    • "An efficient one-pot synthesis of coumarins mediated by propylphosphonic anhydride (T3P) via the Perkin condensation", John Kallikat Augustine et al., Tetrahedron Lett. 2012, 53, 4422-4425.
    • "Access and Regioselective Transformations of 6-Substituted 4-Aryl-2,8-dichloropyrido[3,2-d]pyrimidine Compounds", Gwenaelle Bouscary-Desforges et al., J. Org. Chem. 2012, 77, 4586-4595.
    • "Regioselective Synthesis of 2,8-Disubstituted 4-Aminopyrido[3,2-d]pyrimidine-6-carboxylic Acid Methyl Ester Compounds", Gwenaelle Bouscary-Desforges et al., J. Org. Chem. 2012, 77, 243-252.
    • "Development and validation of LC-MS/MS method for the estimation of b-hydroxy-methylbutyrate in rat plasma and its application to pharmacokinetic studies", Parag Deshpandea et al., Biomed. Chromatogr. 2012 (wileyonlinelibrary.com) DOI 10.1002/bmc.2758
  • 2011

    • "Discovery of Potent, Selective, and Orally Bioavailable Alkynylphenoxyacetic Acid CRTH2 (DP2) Receptor Antagonists for the Treatment of Allergic Inflammatory Diseases", Stefano Crosignani et al., J. Med. Chem. 2011, 54, 7299–7317.
    • “The Design, Synthesis and Structure-Activity Relationships of Novel Isoindoline-based Histone Deacetylase Inhibitors” ,1) Shultz, M.; Fan, J.; Chen, C.; Cho, Y.S.; Davis, N.; Bickford, S.; Buteau, K.; Cao, X.; Holmqvist, M.; Hsu, M.; Jiang, L.; Liu, G.; Lu, Q.; Patel, C.; Suresh, J.R.; Selvaraj, M.; Urban, L.; Wang, P.; Yan-Neale, Y.; Whitehead, L.; Zhang, H.; Zhou, L.; Atadja, P.Bioorg. Med. Chem. Lett. 2011, 21, 4909-4912. doi:10.1016/j.bmcl.2011.06.015 .
    • "An efficient catalytic method for the Friedländer annulation mediated by peptide coupling agent propylphosphonic anhydride (T3P)”, Augustine, J. K.; Bombrun, A.; Venkatachaliah, S. Tetrahedron Lett. 2011, 52, 6814-6818. DOI: 10.1016/j.tetlet.2011.10.048
    • "An efficient catalytic method for the Beckmann rearrangement of ketoximes to amides and aldoximes to nitriles mediated by propylphosphonic anhydride (T3P)” ,Augustine, J. K.; Kumar, R.; Bombrun, A.; Mandal, A. B.Tetrahedron Lett. 2011, 52, 1074-1077. DOI: 10.1016/j.tetlet.2010.12.090.
    • “Propylphosphonic Anhydride (T3P)-Mediated One-Pot Rearrangement of Carboxylic acids to Carbamates” ,22) Augustine, J. K.; Bombrun, A.; Mandal, A. B.; Alagarsamy, A.; Atta, R. N.; Selvam, P. Synthesis 2011, 1477-1483. DOI: 10.1055/s-0030-1259964.
    • “A practical and cost efficient one-pot conversion of aldehydes to nitriles mediated by activated DMSO” ,Augustine, J. K.; Bombrun, A.; Atta, R. N.Synlett. 2011, 2223-2227. DOI: 10.1055/s-0030-1261181 .
    • “Tricyclic pyrazol amine derivatives” ,WO2011/058149A1 (2011) Gaillard, P.; Jeanclaude-Etter, I.; Pomel, V.; Sebille, E.; Seenisamy, J.; Muzerelle, M.

  • 2010
    • "Rhodium-Catalyzed Asymmetric Hydrosilylation of Ketones Employing a New Ligand Embodying the Bis(oxazolinyl)pyridine Moiety". Atanu Ghoshal et al., Syn. Lett. 10 (2010), 1459-1462.
    • "gem-Dibromomethylarenes as Aldehyde Surrogates in the Pictet-Spengler Synthesis of Tetrahydroisoquinolines and Isoindoloisoquinolones", Nagaraja Chowdappa et al., Synthesis 2010, 17, 2949-2956.
    • "TRICYCLIC PYRAZOL AMINE DERIVATIVES". Gailard et al., WO2011058149 filed on November 2010.
    • "FUSED BICYCLIC COMPOUNDS AS INHIBITORS FOR PI3 KINASE" Swinnen et al., 2010. WO2010100144 filed on March, 2010.
  • 2009
    • "Propylphosphonic anhydride (T3P): an efficient reagent for the one-potsynthesis of 1,2,4-oxadiazoles, 1,3,4-oxadiazoles, and 1,3,4-thiadiazoles", John Kallikat Augustine et al., Tetrahedron 2009, 65, 9989-9996.
    • "Di-tert-butyl dicarbonate: a versatile carboxylating reagent", John Kallikat Augustine et al., Tetrahedron 2009, 65, 134-138.
    • "gem-Dibromomethyl Aromatics: Efficient Aldehyde Equivalents in the Knoevenagel-Doebner Reaction", John Kallikat Augustine et al., Synthesis 2009, 14, 2349-2356.
    • "Propylphosphonic Anhydride (T3P): A Remarkably Efficient Reagent for the One-Pot Transformation of Aromatic, Heteroaromatic, and AliphaticAldehydes to Nitriles", John Kallikat Augustine et al., Synlett. 2009, 20, 3378-3382.
    • "PTSA-ZnCl2: An Efficient Catalyst for the Synthesis of 1, 2, 4-Oxadiazoles from Amidoximes and Organic Nitriles", John Kallikat Augustine et al., J. Org. Chem. 2009, 74, 5640–5643.
    • "Mild oxidation of alcohols with periodic acid catalyzed by [Ru(acac)2(CH3CN)2]PF6 in water", S. Ganesamoorthy et al., Catalysis Communications 10(14), 1835-1838 (2009).
  • 2008
    • "An Unusual Reaction of Benzalaminoacetals in Trifluoroacetic Acid: Facile Synthesis of 2-Benzylpyrazines", John Kallikat Augustine et al., J. Org. Chem. 2008, 73, 1176-1179.
    • "A versatile method for the hydrolysis of gem-dibromomethylarenes bearing carboxylate or boronate group into aldehydes", John Kallikat Augustine et al., Tetrahedron 2008, 64, 688-695.
    • "Novel and Highly Regioselective Friedel-Crafts Alkylation of 3, 5-Dimethoxyaniline Using an Aldehyde and Triethylsilane as Reducing Agent", John Kallikat Augustine et al., Synlett. 2008, 16, 2429-2432.
  • 2007

    "gem-Dibromomethylarenes: A Convenient Substitute for Noncommercial Aldehydes in the Knoevenagel-Doebner Reaction for the Synthesis of a, ß-Unsaturated Carboxylic Acids", John Kallikat Augustine et al., J. Org.

  • 2006

     "Selective one-pot synthesis of Z-iodoallylic iodides from propargyl alcohols". Manickam G et al., 47 (33) [2006], 5867-5868.

  • 2005

    "The expedient access to bromo-pyridine carbaldehyde scaffolds using gem-dibromomethyl intermediates", Ashis Baran Mandal et al., Tetrahedron Lett. 2005, 46, 6033-6036.

  • 2004

    "Synthesis of Sulfonamide Derivatives", John Kallikat et al., Patent: WO 2004/020401 A1.

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