Putting Science to Work

Genomics and Translational Biology

Genomics & Translational Biology

The Genomics & Translational Biology group provides services that cater to the continuum of drug discovery programs, as well as other applications that involve the characterization and quantification of DNA or RNA.

Genomics & Translational Biology

We are equipped with a 96 capillary DNA analyser (ABI) for Sanger sequencing and two platforms (Illumina™ MiSeq and Illumina™ NextSeq) for Next-Generation Sequencing (NGS).

NGS technology enables profiling of DNA and RNA at very high throughputs and high resolution to address a variety of biological questions. The technology can be exploited at early discovery stages (Lead identification, target-discovery, validation, mechanism of action); as well as during later stages (In vitro/in vivo studies, tumor biology, PDx models, biomarker discovery, genome editing, CDx development, patient stratification for trial design, drug repurposing).

The Syngene NGS facility offers a range of sequencing services that include the following:

  • Whole Genome Sequencing (De novo and resequencing)
  • Targeted Resequencing (custom amplicon panels)
  • Exome Sequencing
  • Transcriptome Sequencing
  • ChIP-Sequencing
  • Microbiome sampling by 16s rDNA sequencing
  • Whole Genome Shotgun Metagenomics

Our services include initial experimental design, sample processing (library preparation), sequencing, and tiered analysis based on requirements of the client.

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