Putting Science to Work
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Battery of Genetic Toxicology Studies

Syngene routinely conducts IND enabling studies and the following in vitro and in vivo gentox studies to support candidate selection.

  • Studies from 7-days to 6-months in duration
  • Bacterial reverse mutation test (Ames test)
  • In vitro Chromosome aberration test in CHO cell lines and Human Peripheral Blood Lymphocytes
  • In vitro Micronucleus Test in CHO cell lines and Human Peripheral Blood Lymphocytes
  • Micronucleus test in rodents (rats and mice)
  • Chromosomal aberration test in rodents (rats and mice)

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