Battery of Genetic Toxicology Studies
Syngene routinely conducts IND enabling studies and the following in vitro and in vivo gentox studies to support candidate selection.
- Studies from 7-days to 6-months in duration
- Bacterial reverse mutation test (Ames test)
- Chromosome aberration test (in vitro) in CHO cell lines
- Micronucleus test in rodents (rats and mice)