What is Whole Genome Sequencing (WGS)?
WGS is a DNA-Seq technology that focuses on complete genome of an organism. It includes exons, introns, intragenic regions and mitochondria. Therefore, WGS analysis can be an excellent approach when there is a scope beyond genes in sequencing. It is used for sequencing any species, including livestock, plants, or disease-related microbes.
WGS analysis detects structural variants (e.g., gene fusions), CNVs and large indels with high sensitivity. For novel organisms, WGS gives a path for assembling its novel genome through de novo approach. WGS plays a key role in GWAS studies and clinical diagnosis.
What is Targeted Sequencing?
Targeted sequencing is a DNA-Seq technology that focuses on specific regions of the genome. Exons or introns, or any intergenic regions of a gene or specific group of genes can be interrogated using this approach. Therefore, targeted sequencing analysis can be an excellent approach when there is already a foundation of candidate genes that are of interest.
Syngene’s variant calling pipeline
Genome Sequencing standard deliverables