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Our decarbonisation efforts are translating into tangible results reducing our climate impact while strengthening operational efficiency.
Target achieved, driven by our commitment and investment in renewable energy
Total Scope 1 and Scope 2 emission intensity in terms of physical output
Total GHG savings as a result of efficiency measures
Achieved annual emission reduction in FY25
Balance emissions remaining to target
Scope 1 & 2 emissions reduction against a 54.6% target
Efficient energy use remains a core pillar of our sustainability strategy. We continued to focus on optimizing energy consumption, integrating renewable sources, and adopting advanced technologies that deliver both environmental and economic benefits. We remain focused on achieving our goal of sourcing 96% of our energy from renewable sources by 2028.
energy from renewable sources
of GHG emissions avoided
GHG emissions
(Scope 1 and Scope 2) offset
Wind power plant capacity
Solar power plant capacity
(100% in-house) Solar rooftop capacity
Wind power plant capacity
Solar power plant capacity
Solar rooftop capacity
Water is vital to our operations, and strategic management is key to long-term sustainability. To address regional water challenges, we have adopted advanced recycling, rainwater harvesting, and on-site storage solutions to reduce dependency on external sources.
Year-on-Year freshwater savings
Fresh water saved through rainwater harvesting and water recycling
Rainwater harvested
Mangalore and Bangalore sites
At Syngene’s Bengaluru campus, a dedicated 4,000 sq. ft. facility manages non-hazardous, hazardous, and biomedical waste. Hazardous waste is collected in leak-proof containers, segregated by type, and either recycled or incinerated to prevent contamination. Hyderabad campus features secure, designated zones for each waste category, with all activities conducted under standard operating procedures aligned with local regulations. In Mangaluru, hazardous waste is managed through both onsite and offsite facilities, categorized by material compatibility. Since April 2025, Syngene has transitioned from manual logbooks to an online waste declaration system, enabling real-time data entry, improving accuracy, and ensuring easy access to waste generation records.
hazardous and non- hazardous
waste recycled
maintained across all Syngene
operational control sites
We have begun transitioning to recycled paper across our Bengaluru and Hyderabad campuses. Our Hyderabad office now uses 100% FSC (Forest Stewardship Council) certified recycled A4 paper for all printing. We have also introduced eco-friendly products, such as plantable notebooks, pens, and pencils that will grow into plants after use, encouraging environmentally conscious habits across our teams.
Energy
Sourcing from renewable power
Water
Reduction in freshwater consumption
Waste
Recycling of waste to be maintained
Greenhouse gas emission reduction
Reduction in GHG emissions by FY 2033
Green chemistry is a sustainable approach that reduces carbon footprint while improving manufacturing efficiency. In labs, this means rethinking traditional chemistry methods to make them safer, more efficient, and less wasteful. By transforming our processes, we are reducing environmental impact and driving sustainable innovation in the industry.
We initiated a major step forward by partnering with My Green Lab (MGL), a globally recognized non-profit organization. We launched a pilot project involving three laboratories, two from Research Services and one from the Chemical Development division to pursue My Green Lab certification. Over the course of eight months, our teams undertook a collaborative journey, embedding changes in lab behavior, resource usage, and infrastructure. In July 2025, all three labs achieved Green Level Certification, the highest rating awarded by MGL, with outstanding scores:
98% - Synopolis FC Lab
95% - Cell Culture TC-1
94% - S1 SF Chemical Development Lab
This marks a strong start toward scaling sustainable practices across more labs in the future.
Syngene has joined the American Chemical Society Green Chemistry Institute Pharmaceutical Roundtable (ACSGCIPR) as an associate member. Through this platform, we gain access to insights from leaders such as Pfizer, AstraZeneca, GSK, and Novartis, who are pioneering greener approaches for complex modalities like peptides, oligonucleotides, and antibody-drug conjugates. We are also engaging with emerging technologies such as photoredox and electrochemistry, increasingly combined with flow chemistry to reduce resource use and environmental impact.
Environmental stewardship is not just a commitment, at Syngene; it is a journey toward a greener, sustainable future. We prioritize green spaces across all campuses to support employee well-being and ecological balance.
To mark World Environment Day and Earth Day, employees participated in plantation drives across Bengaluru, Hyderabad, and Mangaluru. Initiatives included transforming barren forest land in Bhoothanahalli, funding Miyawaki microforests in Mangaluru, and restoring green zones in collaboration with local authorities. These efforts promote long-term carbon sequestration, drought resilience, and biodiversity enhancement.
Our Environment, Health and Safety (EHS) Policy reflects our strong 'Goal Zero' commitment, aiming for zero harm to people, the planet, and physical assets. Grounded in international standards like ISO 14001 and ISO 45001, the policy is actively implemented through regular risk assessments, internal audits, employee training, and multilingual awareness campaigns.
To develop a greener alternative to traditional chemo-catalytic hydrogenation processes that typically involve hazardous reagents, high energy input, and environmental risks.
Syngene engineered a biocatalytic process using ene-reductase enzymes for enantioselective hydrogenation of activated alkenes. This method operates under mild conditions - ambient temperature and pressure, using water-based media, glucose as a renewable electron donor, and an in-situ cofactor regeneration system. The process minimizes the use of organic solvents (only 10%) and eliminates the need for flammable hydrogen gas and precious metal catalysts.
The enzymatic process achieved >99% enantiomeric excess, significantly reduced energy consumption, and lowered hazardous waste generation. It enhanced operational safety and environmental responsibility.
To enhance the scalability, safety, and sustainability of a rare disease molecule manufacturing process for an American biotechnology partner.
Following early-stage screening, Syngene identified key inefficiencies - low yield, high Process Mass Intensity (PMI), safety risks, and extended cycle time. A targeted strategy was implemented involving closed-loop systems, solvent substitution, direct crystallization, and telescopic process integration to improve control and throughput.
The optimized process reduced cycle time by 50%, increased yield by 26%, and improved product purity to >97%. Replacing Class 2 solvents with Class 3 process-friendly solvents and adopting solvent recovery techniques. The result was a robust, scalable, and eco-friendly process, with the advantages of reduced waste, improved yields, favoring the reduction of cycle times.
To develop a sustainable alternative to heat-intensive C(sp²)–C(sp³) couplings using photoredox-enabled decarboxylative cross-coupling under ambient conditions.
The team optimized reaction parameters - base selection (BTMG (2-tert-Butyl-1,1,3,3-tetramethylguanidine)), dilution, light source (456 nm BLED (Blue Light-Emitting Diode)), and temperature control (~35°C), to improve conversion and selectivity. TLC (Thin-Layer Chromatography) and LC-MS (Liquid Chromatography-Mass Spectrometry) confirmed minimal impurities and high product formation.
To redesign a robust but resource-intensive scale-up process by reducing solvent use, hazardous reagents, and waste, while improving yield and operational safety.
The scientific and engineering teams collaborated to implement carbon treatment with Class 3 solvents, direct crystallization, and telescopic process integration. Equipment modifications and solvent recovery strategies were prioritized to enhance safety and sustainability.
The redesigned process reduced cycle time by 50%, increased yield by 26%, and significantly lowered solvent volume and waste. Replacing carcinogenic solvents with safer alternatives improved environmental performance.
To develop a stable, high-performance specialty polymer for green energy applications, overcoming molecular instability and scale-up challenges.
Syngene’s Performance & Specialty Materials team conducted root cause analysis and redesigned the polymer’s molecular structure. A complex multi-step synthesis was transformed into a scalable single-pot process. Scale-down studies enabled successful production in multi-feet rolls.
The polymer demonstrated over 10,000 hours of consistent performance. Kraton launched a stable, scalable polymer for green energy, gaining first-mover advantage in the specialty film segment. The collaboration secured Kraton’s first-mover advantage in the specialty polymer film industry, providing them a competitive edge.
To embed sustainability in Syngene’s supply chain by integrating ESG practices and advancing supplier alignment with SBTi.
Led by the Strategic Sourcing team and sponsored by the CFO and CPO, Syngene advanced sustainable procurement through the EcoElevate program, assessing and training 200+ suppliers (~44% of spend) on ESG parameters under the Suppliers’ Chapter and upskilling 100+ internal buyers under the Employees’ Chapter. The company also launched a supplier decarbonization program covering 82% of Scope 3 emissions suppliers to advance towards our Science Based Initiatives (SBTi) targets. Additionally, we introduced a Supplier Diversity Policy, and joined the Pharmaceutical Supply Chain Initiative (PSCI) to strengthen responsible sourcing and align with global ESG standards.
Engaging suppliers with varying ESG maturity, ensuring timely participation in training and assessments, and aligning internal teams on governance and reporting requirements were key challenges.
Syngene’s EcoVadis score rose from 40 to 77, and the company achieved a verified ISO 20400 statement. ESG assessments now cover 44% of supplier spend, and a target of 81.6% supplier alignment with SBTi by 2028 strengthens governance, transparency, and overall supply chain resilience.
To enhance safety in hazardous solvent handling and reduce freshwater consumption through innovative engineering solutions.
The Hyderabad facility introduced Earth Rite systems to eliminate ignition risks during flammable liquid transfers, improving safety and operational efficiency. In parallel, a closed-loop scrubber recirculation system was implemented to continuously recycle water, reducing dependency on freshwater resources.
The Earth Rite system significantly improved safety in solvent handling. The optimized scrubber system led to a 40% reduction in process water usage. Our progress in Hyderabad sets a benchmark for future endeavors, fostering a culture where safety, efficiency, and sustainability thrive together.
To reduce energy consumption and operational costs across Syngene’s facilities by implementing energy-efficient solutions in ventilation, cooling, air conditioning, and pumping systems.
Targeted interventions were implemented across multiple systems:
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